In the first installment of this four-part series on the Clinical Research in Rare Diseases, our Medics take a closer look at the developing treatments and therapeutic challenges of Adult Onset Still’s Disease (AOSD). “Adult onset Still’s disease (AOSD) is a rare inflammatory joint disease of unknown aetiology characterised by arthritis, fevers spiking once or […]

 

 

 

In this issue of our newsletter, you can read more about the Clinical Development in Rare Diseases. The first article in a four-part series regarding rare diseases. Our Medics take a closer look at treatment, therapeutic challenges and Clinical Development associated with Idiopathic Pulmonary Fibrosis (IPF): “Idiopathic pulmonary fibrosis (IPF) is a rare disease, which affects […]

 

 

 

In the final installment of this four-part series on the Clinical Development in Challenging Cancers, our Medics take a closer look at the developing treatments and therapeutic challenges of Cholangiocarcinoma (CCA): “CCA is considered to be the second most frequent primary hepatobiliary malignancy after hepatocellular carcinoma (HCC)4. Due to the uneven distribution of risk factors, […]

 

 

 

In the third article in the series. Our Medics take a closer look at treatment, therapeutic challenges and Clinical Development in Ovarian Clear Cell Carcinoma (OCCC): “Ovarian clear cell carcinoma (OCCC) is a rare histological subtype of epithelial ovarian cancers (EOCs), with an incidence, among EOCs, of 4-12% in Western countries [1–3] and a higher […]

 

 

 

In this second article of the four part series, you can read and find more information about Primary Bone Sarcomas that are considered as an extremely rare type of cancers. “Primary bone sarcomas are cancers of mesenchymal, non-epithelial derivation, originating from bone cells or their precursors. As shown in Figure 1, the most common forms […]

 

 

 

In this article, our Medical Experts explore the concept of “Pragmatic Clinical Trials” as a research approach that supports determining the effectiveness of an intervention to facilitate decision making in day-to-day clinical practice. “Explanatory trials generally measure efficacy which reflects on the benefit a treatment produces under ideal conditions, usually employing carefully selected participants in […]

 

 

 

In this first article of four, our Medics take a closer look at Adrenocortical Carcinoma, treatment of this rare type of cancer and future prospects based on Immunotherapy. “Adrenocortical carcinoma (ACC) is a rare cancer with an estimated incidence of 1 to 2 patients per million people annually [1-3], and one in which most patients, […]

 

 

Medical Management In Clinical Trials. Part 4: Close-Out Phase  2016 started as a promising year with many exciting projects with which Europital medical experts would be able to accomplish two of their principal endeavors: knowledge building and information sharing. As a result, during this period a large number of scientific articles have been published in […]

 

 

Knowledge building and information sharing pertain to the founding vision  at Europital. “Medical Management in Clinical Trials: A Roadmap to Operational Excellence” is series of articles hat discourse about the role of the responsible Medical Monitor during the various milestones of a clinical trial. In this third article of the Medical Management series, the various monitoring activities […]

 

 

Medical Management process
We previously introduced you to “Medical Management in Clinical Trials: A Roadmap to Operational Excellence”, which represents the first article of a series that discourse about the role of the responsible Medical Monitor during the various milestones of a clinical trial. While the first part was focused on the Development Phase of a Clinical Trial […]