In the final installment of this four-part series on the Clinical Development in Challenging Cancers, our Medics take a closer look at the developing treatments and therapeutic challenges of Cholangiocarcinoma (CCA): “CCA is considered to be the second most frequent primary hepatobiliary malignancy after hepatocellular carcinoma (HCC)4. Due to the uneven distribution of risk factors, […]




In the third article in the series. Our Medics take a closer look at treatment, therapeutic challenges and Clinical Development in Ovarian Clear Cell Carcinoma (OCCC): “Ovarian clear cell carcinoma (OCCC) is a rare histological subtype of epithelial ovarian cancers (EOCs), with an incidence, among EOCs, of 4-12% in Western countries [1–3] and a higher […]




In this second article of the four part series, you can read and find more information about Primary Bone Sarcomas that are considered as an extremely rare type of cancers. “Primary bone sarcomas are cancers of mesenchymal, non-epithelial derivation, originating from bone cells or their precursors. As shown in Figure 1, the most common forms […]




In this article, our Medical Experts explore the concept of “Pragmatic Clinical Trials” as a research approach that supports determining the effectiveness of an intervention to facilitate decision making in day-to-day clinical practice. “Explanatory trials generally measure efficacy which reflects on the benefit a treatment produces under ideal conditions, usually employing carefully selected participants in […]




In this first article of four, our Medics take a closer look at Adrenocortical Carcinoma, treatment of this rare type of cancer and future prospects based on Immunotherapy. “Adrenocortical carcinoma (ACC) is a rare cancer with an estimated incidence of 1 to 2 patients per million people annually [1-3], and one in which most patients, […]



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